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TETRAD FACULTY
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Drosophila and Drugs of Abuse
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Our laboratory uses the fruitfly Drosophila melanogaster as model system to study behaviors induced by addictive drugs, such as alcohol, nicotine, and cocaine. We have developed assays that allow the quantification of these behaviors and have isolated mutants that respond abnormally to drug exposure. In addition to defining drug-induced behaviors and their genetic control, we have begun to map the neuroanatomical sites of drug action and their relation to specific behaviors. Integrating the information gained from behavioral, genetic, molecular, and neuroanatomical analyses will help us gain an understanding of drug-induced behaviors in flies and, eventually, in mammals.
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Faculty
