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Drosophila sensory neurons tile the larval body wall, Dr. Chun Han

Faculty

Office: 
Campus Address: CVRI - 214 Box: 3118
Phone: 
(415) 476-8821

Thomas Kornberg

Drosophila developmental genetics

We investigate mechanisms that pattern developing organs, focusing on the morphogen signaling proteins that are responsible for pattern formation, on the processes that regulate their expression and activity and on the manner by which they move from producing to target cells. We address these questions in Drosophila using a variety of genetic, molecular genetic and biochemical approaches.  Among the current projects are studies of Hedgehog signaling, the roles and properties of cytonemes (specialized filopodia that transport morphogen signaling proteins between cells), and gene expression and development of the early, pre-blastoderm embryo.