Journal Club Talk 1/12/22

Event Date: 
Wednesday, January 12, 2022 - 1:00pm

GH N114 (indoor masking required) and Class Capture

Brandon Courteau
Jura/Verba Lab

“It’s Not Just a Phase Mom: Phase separation of a critical phosphatase promotes MAPK activation”

Zhu G, Xie J, Kong W, Xie J, Li Y, Du L, Zheng Q, Sun L, Guan M, Li H, Zhu T, He H, Liu Z, Xia X, Kan C, Tao Y, Shen HC, Li D, Wang S, Yu Y, Yu ZH, Zhang ZY, Liu C, Zhu J. Phase Separation of Disease-Associated SHP2 Mutants Underlies MAPK Hyperactivation. Cell. 2020 Oct 15;183(2):490-502.e18. Epub 2020 Sep 30. PMID: 33002410; PMCID: PMC7572904.
 
Martin Kampmann
 
"Sweet old brain: In vitro and in vivo CRISPR-Cas9 screens reveal drivers of aging in neural stem cells of the brain"
 
Ruetz et al. In vitro and in vivo CRISPR-Cas9 screens reveal drivers of aging in neural stem cells of the brain. bioRxiv 2021.11.23.469762.