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Journal Club

Journal Club: Wednesdays at 1:00pm in Genentech Hall Auditorium

September 26, 2018

***Will meet in GH N114***

Joy Li
von Zastrow Lab

“Goldilocks and the introns: H2A.Z helps optimize kinetic coordination of cotranscriptional splicing”

Neves LT, Douglass S, Spreafico R, Venkataramanan S, Kress TL, Johnson TL. The histone variant H2A.Z promotes efficient cotranscriptional splicing in S. cerevisiae. Genes Dev. 2017 Apr 1;31(7):702-717. doi: 10.1101/gad.295188.116.

Max Nachury

“Microtubule dynamics: no longer just at the ends”

Vemu A, Szczesna E, Zehr EA, Spector JO, Grigorieff N, Deaconescu AM, Roll-Mecak A. Severing enzymes amplify microtubule arrays through lattice GTP-tubulin incorporation. Science. 2018 Aug 24;361(6404). pii: eaau1504. doi: 10.1126/science.aau1504.

October 3, 2018

Clara Herrera
Engel Lab

"Poxviruses deregulate mTOR activity to evade host cytoplasmic sensors"

Meade N, Furey C, Li H, Verma R, Chai Q, Rollins MG, DiGiuseppe S, Naghavi MH, Walsh D. Poxviruses Evade Cytosolic Sensing through Disruption of an mTORC1-mTORC2 Regulatory Circuit. Cell. 2018 Aug 23;174(5):1143-1157.e17. doi: 10.1016/j.cell.2018.06.053. Epub 2018 Aug 2.

Amanda Chung
Gilbert/Panning Labs

“HEY! LOOK! LISTEN! An environment-to-epigenome Link between diabetes and cancer via AMPK and TET2”

Wu D. et al. Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer. Nature. 2018 Jul;559(7715):637-641. doi: 10.1038/s41586-018-0350-5. Epub 2018 Jul 18.



October 10, 2018

Varun Bhadkamkar
Mukherjee Lab



Leor Weinberger