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Drosophila sensory neurons tile the larval body wall, Dr. Chun Han


Campus Address: CVRI 452W Box 3122
(415) 514-1133

Natalia Jura

Membrane Organization and Control of Signaling

Cellular signaling is initiated through highly specific assembly of the supramolecular membrane complexes involving receptor tyrosine kinases that integrate incoming signals into biological responses. We are just beginning to understand how these complexes come together and regulate activation of their multiple components. In order to uncover missing molecular insights into signal transduction and understand how plasma membrane organizes cellular signaling, we use single molecule membrane reconstitution methods and combine structural and cell biology with high resolution imaging.