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Drosophila sensory neurons tile the larval body wall, Dr. Chun Han

Faculty

Office: 
Campus Address: GH, N-312E Box: 2200
Phone: 
(415) 476-6380

Courses Taught

Ron Vale

Molecular Motors

The Vale Lab combines cell biological and biophysical approaches to understand the cytoskeleton and more general issues on spatial organization and movement within cells. The lab, which relies heavily on microscopy, studies these questions at different scales and using different techniques. At the smallest scale, we wish to understand the workings of protein machines. A particular focus has been on microtubule-based "motor proteins", 10-50 nm size proteins, that convert energy from ATP hydrolysis into unidirectional motion and force. However, we also are studying the mechanism of other types of proteins, such as microtubule severing proteins, proteins that localize dynamically to growing plus ends of microtubules (+TIPs), and motor regulatory proteins.