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Events

Seminars: Tuesdays at 4:00pm in Genentech Hall Auditorium

September 26, 2017

Elçin Ünal

UC Berkeley

“Meiotic Differentiation: Uncovering Unique Modes of Gene Regulation and Organelle Remodeling”

October 24, 2017

Andrew Holland

Johns Hopkins University

“Once and only once: Mechanisms of centriole duplication and their deregulation in disease”

October 31, 2017

Gary Ruvkun

Harvard

“C. elegans surveillance of conserved cellular components to detect and defend pathogen attacks, real or imagined

November 14, 2017

Sebastian Lourido

MIT, Whitehead Institute

“Genome-Wide Approaches to Unlock the Mysteries of Apicomplexan Parasitism"

Journal Club: Wednesdays at 1:00pm in Genentech Hall Auditorium

September 27, 2017

***Will meet in Genentech Hall N114***

Taylor Skokan
Vale Lab

"Finding closure after a break up:  Identifying a key regulator of nuclear envelope reformation after chromosome segregation”

Samwer M, Schneider MWG, Hoefler R, Schmalhorst PS, Jude JG, Zuber J, Gerlich DW.  DNA Cross-Bridging Shapes a Single Nucleus from a Set of Mitotic Chromosomes. Cell. 2017 Aug 24;170(5):956-972.e23. doi:10.1016/j.cell.2017.07.038.

Hiten Madhani

"Two men say they're Jesus.  One of them must be wrong”

Gladyshev E, Kleckner N. DNA sequence homology induces cytosine-to-thymine mutation by a heterochromatin-related pathway in Neurospora. Nat Genet. 2017 Jun;49(6):887-894. doi: 10.1038/ng.3857. Epub 2017 May 1.

October 4, 2017

***Will meet in Genentech Hall N114***

Paige Haas
Krogan Lab

“Use the Force: Mechanical cues initiate self-organization in avian skin development”

Shyer AE, Rodrigues AR, Schroeder GG, Kassianidou E, Kumar S, Harland RM. Emergent cellular self-organization and mechanosensation initiate follicle pattern in the avian skin. Science. 2017 Aug 25;357(6353):811-815. doi: 10.1126/science.aai7868. Epub 2017 Jul 13.

Sophie Dumont

“On Being Big: Large Cytoplasm Is Linked to the Error-Prone Nature of Oocytes”

Kyogoku H, Kitajima TS. Large Cytoplasm Is Linked to the Error-Prone Nature of Oocytes. Dev Cell. 2017 May 8;41(3):287-298.e4. doi: 10.1016/j.devcel.2017.04.009.

October 11, 2017

***Will meet in Genentech Hall N114***

Senen Mendoza
Bondy-Denomy Lab

“The apple doesn’t fall far from the tree: replication-coupled modification in plants”

Jiang D, Berger F. DNA replication-coupled histone modification maintains Polycomb gene silencing in plants. Science. 2017 Sep 15;357(6356):1146-1149. doi: 10.1126/science.aan4965. Epub 2017 Aug 17.

Joe Bondy-Denomy

“Gene editing without CRISPR! Worm brains figured it out a long time ago”

Deffit SN, Yee BA, Manning AC, Rajendren S, Vadlamani P, Wheeler EC, Domissy A, Washburn MC, Yeo GW, Hundley HA. The C. elegans neural editome reveals an ADAR target mRNA required for proper chemotaxis. Elife. 2017 Sep 19;6. pii: e28625. doi: 10.7554/eLife.28625. [Epub ahead of print]
October 25, 2017

***Will meet in Genentech Hall N114***

Myles Hochman
Goodarzi Lab

“RNA Editing in Cephalopods Linked to Changes in Ink-remential Rate of Genomic Evolution”

Liscovitch-Brauer N, Alon S, Porath HT, Elstein B, Unger R, Ziv T, Admon A, Levanon EY, Rosenthal JJ, Eisenberg E.  Trade-off between Transcriptome Plasticity and Genome Evolution in Cephalopods. Cell. 2017 Apr 6;169(2):191-202.e11. doi: 10.1016/j.cell.2017.03.025.

Bassem Al-Sady

“Never forget the depth of winter: How heterochromatin spreading makes sure you remember”

Yang H, Berry S, Olsson TSG, Hartley M, Howard M, Dean C. Distinct phases of Polycomb silencing to hold epigenetic memory of cold in Arabidopsis. Science. 2017 Sep 15;357(6356):1142-1145. doi: 10.1126/science.aan1121. Epub 2017 Aug 17.

November 1, 2017

Antonio Cuevas-Navarro
McCormick Lab

“One Step Closer to Designer Antlings”

Yan H et al. An Engineered orco Mutation Produces Aberrant Social Behavior and Defective Neural Development in Ants. Cell. 2017 Aug 10;170(4):736-747.e9. doi: 10.1016/j.cell.2017.06.051.

Martin Kampmann

“This mechanism of selective vulnerability is dope! (amine)”

Burbulla LF et al. Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson's disease. Science. 2017 Sep 22;357(6357):1255-1261. doi: 10.1126/science.aam9080. Epub 2017 Sep 7.

November 8, 2017
***Will meet in Genentech Hall N114***

Kristine Trotta
Chous Lab

"Another Runner in the Night: A Novel Strategy for Propagation of Selfish Genetic Elements”

Tiwari B, Kurtz P, Jones AE, Wylie A, Amatruda JF, Boggupalli DP, Gonsalvez GB, Abrams JM. Retrotransposons Mimic Germ Plasm Determinants to Promote Transgenerational Inheritance. Curr Biol. 2017 Oct 9;27(19):3010-3016.e3. doi: 10.1016/j.cub.2017.08.036. Epub 2017 Sep 28.

Steve Altschuler

“Drug-sensitivity measures that grow better with time”

Hafner M, Niepel M, Chung M, Sorger PK. Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs. Nat Methods. 2016 Jun;13(6):521-7. doi: 10.1038/nmeth.3853. Epub 2016 May 2.
November 15, 2017

***Will meet in Genentech Hall N114***

Chris McGinnis
Gartner Lab

“Optogenetic induction of neuronal differentiation sheds light on how cells distinguish signal from noise during fate selection”

Sokolik C, Liu Y, Bauer D, McPherson J, Broeker M, Heimberg G, Qi LS, Sivak DA, Thomson M. Transcription factor competition allows embryonic stem cells to distinguish authentic signals from noise. Cell Syst. 2015 Aug 26;1(2):117-129.

Todd Nystul

“RNA methylation is the new kid on the block”

Cui Q, Shi H, Ye P, Li L, Qu Q, Sun G, Sun G, Lu Z, Huang Y, Yang CG, Riggs AD, He C, Shi Y. m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells. Cell Rep. 2017 Mar 14;18(11):2622-2634. doi: 10.1016/j.celrep.2017.02.059.

November 29, 2017

***Will meet in Genentech Hall N114***

Bushra Bibi
Joachim Li Lab

“Actin actin-g up in the spindle…Really?”

Mogessie B, Schuh M. Actin protects mammalian eggs against chromosome segregation errors. Science. 2017 Aug 25;357(6353). pii: eaal1647. doi: 10.1126/science.aal1647.

Robert Edwards

“Protein Homeostasis in the Normal State”

Li J, Zhang YV, Asghari Adib E, Stanchev DT, Xiong X, Klinedinst S, Soppina P, Jahn TR, Hume RI, Rasse TM, Collins CA. Restraint of presynaptic protein levels by Wnd/DLK signaling mediates synaptic defects associated with the kinesin-3 motor Unc-104. Elife. 2017 Sep 19;6. pii: e24271. doi: 10.7554/eLife.24271.

Thesis Talks

December 6, 2017
December 6, 2017

Genenetech Hall N114 — 3:00PM

Adam Larson
Narlikar Lab

"TBA"

December 7, 2017

Rock Hall Auditorium — 3:00PM

Walter Huynh
Vale Lab

"TBA"

December 12, 2017

Rock Hall Auditorium — 2:00PM

Liz Costa
Weissman Lab

"TBA"

December 13, 2017

Genenetech Hall N114 — 3:30PM

Daniel Elnatan
Agard Lab

"TBA"

December 18, 2017

Medical Sciences N-217 — 2:00PM

Rebecca Kim
Nystul Lab

TBA