Faculty

David Agard, PhD

Research Summary:
Structure, Function, and Folding of Proteins, Chromosomes, and Centrosomes

Nadav Ahituv, PhD

Research Summary:
Functional genomics of gene regulation

Bassem Al-Sady, PhD

Research Summary:
Mechanisms of formation and fidelity of epigenetic elements

Steven Altschuler, PhD

Research Summary:
Systems biology and pharmacology

Raul Andino-Pavlovsky, PhD

Research Summary:
RNA Viruses, Replication, Pathogenesis and Control

Kaveh Ashrafi, PhD

Research Summary:
Metabolic Regulation of Neural Function

Alan Ashworth, PhD

Research Summary:
Understanding the genes that drive breast cancer risk

Roland Bainton, MD, PhD

Research Summary:
The Biology of Chemical Protection

Brian Black, PhD

Research Summary:
Cardiovascular Development

Robert Blelloch, MD, PhD

Research Summary:
Stem Cell Differentiation and Cancer

Joseph Bondy-Denomy, PhD

Research Summary:
CRISPR-Cas Biology and Phage-Bacteria Interactions

David Booth,

Research Summary:
Evolution of cell identity and fate

Katja Brueckner, PhD

Research Summary:
Hematopoiesis and cell signaling

Benoit Bruneau, PhD

Research Summary:
Transcriptional regulation of heart development

Daniele Canzio, PhD

Research Summary:
Transcriptional and post-transcriptional mechanisms generating neural cell-surface diversity

Andy Chang, PhD

Research Summary:
Mechanisms of oxygen and metabolic sensing

Fred Chang, PhD, MD

Research Summary:
Regulation of Cell Size and Shape

Yifan Cheng, PhD

Research Summary:
Structural biology, cryoEM

Seemay Chou, PhD

Research Summary:
Structural and molecular basis of host-microbe interactions

Pao-Tien Chuang, MD, PhD

Research Summary:
Hedgehog Signaling in Mammalian Embryogenesis and Postnatal Physiology

Bruce Conklin, MD

Research Summary:
Signaling and Functional Genomics

Abigail (Abby) Buchwalter Cool, PhD

Research Summary:
Cell biology of the genome

Charles Craik, PhD

Research Summary:
Chemical Biology of Proteases and Their Receptors

Jason Cyster, PhD

Research Summary:
Lymphocyte Migration and Selection

Grae Davis, PhD

Research Summary:
Synapse Formation, Growth and Plasticity

Markus Delling, PhD

Research Summary:
Primary cilia signaling during development and disease

Joe Derisi, PhD

Research Summary:
Genomics and Infectious Disease

Rik Derynck, PhD

Research Summary:
Cell Proliferation and Differentiation

Shawn Douglas, PhD

Research Summary:
DNA nanotechnology

Sophie Dumont, PhD

Research Summary:
Mechanical architecture of cell division

Hana El-Samad, PhD

Research Summary:
Systems Biology of Stress Responses

Joanne Engel, MD, PhD

Research Summary:
Bacterial Pathogen-Host Cell Interactions

Pamela England, PhD

Research Summary:
Chemical Neurobiology: Ion Channel Structure-Function, Synaptic Plasticity

Robert Fletterick, PhD

Research Summary:
Nuclear receptors, transcription factors

Stephen Floor, PhD

Research Summary:
What RNA molecules do after they're made

Alan Frankel, PhD

Research Summary:
RNA-protein complexes

James Fraser, PhD

Research Summary:
Macromolecular structure and dynamics

Adam Frost, PhD, MD

Research Summary:
Structural biology

Jennifer Fung, PhD

Research Summary:
Chromosome Synapsis and Recombination Control During Meiosis

Danica Galonic Fujimori, PhD

Research Summary:
Chromatin, Ribosome, Protein Quality Control

Zev Gartner, PhD

Research Summary:
Tissue structure and function

Luke Gilbert, PhD

Research Summary:
Functional genomics and synthetic biology applied to cancer biology

Andrei Goga, MD, PhD

Research Summary:
Oncogene Signaling

Emily Goldberg, PhD

Research Summary:
Metabolic Regulation of Immune Function

Hani Goodarzi, PhD

Research Summary:
Cancer Systems Biology and Translational Genomics

Douglas Gould, PhD

Research Summary:
Cell-matrix interactions and disease

Carol Gross, PhD

Research Summary:
Regulation of Gene Expression

John Gross, PhD

Research Summary:
Control of eukaryotic mRNA stability

Su Guo, PhD

Research Summary:
Zebrafish Genetics

Bo Huang, PhD

Research Summary:
protein complex; membrane receptor; microscopy

Guo Huang, PhD

Research Summary:
Organ development and regeneration

Holly Ingraham, PhD

Research Summary:
Transcriptional regulators in energy balance

Roshanak Irannejad, PhD

Research Summary:
Organelle-based signaling in cardiovascular biology

Lily Jan, PhD

Research Summary:
Ion channels

Yuh Nung Jan, PhD

Research Summary:
Constructing the nervous system

Alexander-Sandy Johnson, PhD

Research Summary:
Yeast Genetics and Genomics

David Julius, PhD

Research Summary:
Molecular biology

Natalia Jura, PhD

Research Summary:
Structure Function Studies of Cellular Signaling

Martin Kampmann, PhD

Research Summary:
The protein homeostasis network in normal and disease states of human cells

Aimee Kao, MD, PhD

Research Summary:
Lysosome biology and pH dynamics in aging and disease

Yuriy Kirichok, PhD

Research Summary:
Electrical Signaling at the Mitochondrion in Health and Disease

Dave Kokel, PhD

Research Summary:
High-throughput behavior-based neuroactive drug discovery

Tom Kornberg, PhD

Research Summary:
Drosophila developmental genetics

Tanja Kortemme, PhD

Research Summary:
Computational protein design, how proteins function in complex contexts

Nevan Krogan, PhD

Research Summary:
Systems Biology

Pui-Yan Kwok, MD, PhD

Research Summary:
Analysis of Complex Genetic Traits

Noelle L'etoile, PhD

Research Summary:
Neuronal plasticity

Hao Li, PhD

Research Summary:
Computational Genomics

Joachim Li, MD, PhD

Research Summary:
Regulation of Eukaryotic DNA Replication

Wendell Lim, PhD

Research Summary:
Cell signaling; systems and synthetic biology

Averil Ma, MD

Research Summary:
Ubiquitination and cell signaling

Dengke Ma, PhD

Research Summary:
Genetic analysis of biological homeostasis and extremophile

Hiten Madhani, MD, PhD

Research Summary:
Gene expression, genome defense, and pathogenesis

Aashish Manglik, MD, PhD

Research Summary:
Structural biophysics of transmembrane signal transduction

Wallace Marshall, PhD

Research Summary:
How Cells Count and Measure

Frank Mccormick, PhD, FRS

Research Summary:
Ras genes and human cancer

Michael Mcmanus, PhD

Research Summary:
RNAi and Noncoding RNAs

Daniel Minor, PhD

Research Summary:
Ion channel structure and chemical biology

David Morgan, PhD

Research Summary:
Protein Machines That Drive the Cell Cycle

Keith Mostov, MD, PhD

Research Summary:
Epithelial polarity, morphogenesis and regeneration

Shaeri Mukherjee, PhD

Research Summary:
Host-pathogen interactions

Dyche Mullins, PhD

Research Summary:
Dynamics of Structure of the Cytoskeleton

Maxence Nachury, PhD

Research Summary:
Trafficking and signaling at the primary cilium

Geeta Narlikar, PhD

Research Summary:
Mechanisms of Regulating Chromatin Structure and Function

Suzanne Noble, MD, PhD

Research Summary:
The Biology of Candida albicans

Tomasz Nowakowski, PhD

Research Summary:
Development and function of the human brain

Todd Nystul, PhD

Research Summary:
Epithelial stem cells and cancer

Patrick O'farrell, PhD

Research Summary:
Cell cycle control in development

Barbara Panning, PhD

Research Summary:
Stem Cell Epigenetics

Rushika Perera, PhD

Research Summary:
Reprogramming of cellular metabolic networks in cancer

Samuel Pleasure, MD, PhD

Research Summary:
Control of Early Hippocampal Development

Louis Ptacek, MD

Research Summary:
Human Neurogenetics

David Raleigh, PhD, MD

Research Summary:
Developmental biology, lipid signaling and brain tumors

Jeremy Reiter, MD, PhD

Research Summary:
Intercellular communication in development and disease

Oren Rosenberg, MD, PhD

Research Summary:
Molecular pathogenesis of bacteria

John Rubenstein, MD

Research Summary:
Forebrain Development

Davide Ruggero, PhD

Research Summary:
How translational control shapes the proteome in normal and cancer cells

Bjoern Schwer, MD, PhD

Research Summary:
DNA repair and genome stability

Yin Shen, PhD

Research Summary:
Functional genomics and gene regulation

Dean Sheppard, MD

Research Summary:
In vivo functions of integrins

Kevan Shokat, PhD

Research Summary:
Development of Novel Tools to Study Signal Transduction

Anita Sil, MD, PhD

Research Summary:
Fungal Pathogenesis

Daniel Southworth, PhD

Research Summary:
Structure/function of heat shock proteins and protein quality control

Deepak Srivastava, MD

Research Summary:
Molecular Mechanisms of Cardiogenesis

Robert Stroud, MA, PhD

Research Summary:
Cellular Signaling and Molecular Mechanisms

Jack Taunton, PhD

Research Summary:
Actin/Membrane Dynamics and Chemical Proteomics

Thea Tlsty, PhD

Research Summary:
Communal-cell interactions in cancer, genetics, epigenetics

David Toczyski, PhD

Research Summary:
The DNA damage response and ubiquitin-mediated proteolysis

Peter Turnbaugh, PhD

Research Summary:
Impact of the human gut microbiome on pharmacology

Ron Vale, PhD

Research Summary:
Molecular Motors

Mark Von Zastrow, MD, PhD

Research Summary:
Linking Cell Signaling and Membrane Traffic

Peter Walter, PhD

Research Summary:
Mechanisms of Organelle Homeostasis

Leor Weinberger, PhD

Research Summary:
How viruses (and cells) make decisions

Orion Weiner, PhD

Research Summary:
Cell polarity and migration

Arthur Weiss, MD, PhD

Research Summary:
Lymphocyte Signaling and Activation

Jim Wells, PhD

Research Summary:
Apoptosis and Differentiation

Allison Williams,

Research Summary:
Molecular details of signal transduction

Jeremy Willsey, PhD

Research Summary:
Genetic and Systems Biological Approaches to Understanding Neurodevelopmental Disorders

Torsten Wittmann, PhD

Research Summary:
Cytoskeleton dynamics and microscopy

Lani Wu, PhD

Research Summary:
Systems biology and pharmacology

Balyn Zaro, PhD

Research Summary:
Proteomic and chemical biology investigations of innate immunity and hematopoiesis