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Dividing human epithelial cell in a late stage of mitosis, Torsten Wittmann

Student Publications

Mendoza SD, Nieweglowska ES, Govindarajan S, Leon LM, Berry JD, Tiwari A, Chaikeeratisak V, Pogliano J, Agard DA, Bondy-Denomy J. A bacteriophage nucleus-like compartment shields DNA from CRISPR nucleases. Nature. 2020 Jan;577(7789):244-248. doi: 10.1038/s41586-019-1786-y. Epub 2019 Dec 9.
Greenstein RA, Barrales RR, Sanchez NA, Bisanz JE, Braun S, Al-Sady B. Set1/COMPASS repels heterochromatin invasion at euchromatic sites by disrupting Suv39/Clr4 activity and nucleosome stability. Genes Dev. 2020 Jan 1;34(1-2):99-117. doi: 10.1101/gad.328468.119. Epub 2019 Dec 5.
Rosen LE, Klebba JE, Asfaha JB, Ghent CM, Campbell MG, Cheng Y, Morgan DO. Cohesin cleavage by separase is enhanced by a substrate motif distinct from the cleavage site. Nat Commun. 2019 Nov 15;10(1):5189.
Fonseca JP, Bonny AR, Kumar GR, Ng AH, Town J, Wu QC, Aslankoohi E, Chen SY, Dods G, Harrigan P, Osimiri LC, Kistler AL, El-Samad H. A Toolkit for Rapid Modular Construction of Biological Circuits in Mammalian Cells. ACS Synth Biol. 2019 Nov 15;8(11):2593-2606. doi: 10.1021/acssynbio.9b00322. Epub 2019 Nov 5.
Del Cid JS, Reed NI, Molnar K, Liu S, Dang B, Jensen SA, DeGrado W, Handford PA, Sheppard D, Sundaram AB. A disease-associated mutation in fibrillin-1 differentially regulates integrin-mediated cell adhesion. J Biol Chem. 2019 Nov 29;294(48):18232-18243. doi: 10.1074/jbc.RA119.011109. Epub 2019 Oct 22.
Tassetto M, Kunitomi M, Whitfield ZJ, Dolan PT, Sánchez-Vargas I, Garcia-Knight M, Ribiero I, Chen T, Olson KE, Andino R. Control of RNA viruses in mosquito cells through the acquisition of vDNA and endogenous viral elements. Elife. 2019 Oct 17;8. pii: e41244.
Perlaza K, Toutkoushian H, Boone M, Lam M, Iwai M, Jonikas MC, Walter P, Ramundo S. The Mars1 kinase confers photoprotection through signaling in the chloroplast unfolded protein response. Elife. 2019 Oct 15;8. pii: e49577.
Rodriguez L, Voorhies M, Gilmore S, Beyhan S, Myint A, Sil A. Opposing signaling pathways regulate morphology in response to temperature in the fungal pathogen Histoplasma capsulatum. PLoS Biol. 2019 Sep 30;17(9):e3000168.
Qin L, Mizrak A, Guimarães DSPSF, Tambrin HM, Morgan DO, Hall MC. The pseudosubstrate inhibitor Acm1 inhibits the anaphase-promoting complex/cyclosome by combining high-affinity activator binding with disruption of Doc1/Apc10 function. J Biol Chem. 2019 Nov 15;294(46):17249-17261.

Progam

The academic program for the first year includes three laboratory rotations as well as a core curriculum designed to provide students with a foundation for understanding and conducting research in experimental biology. All students take the four core courses during the first two quarters of the first year, and in the third quarter they choose a sequence of three intensive 2-week minicourses.

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