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Drosophila sensory neurons tile the larval body wall, Dr. Chun Han


Box 0520, HD-474
(415) 476-6786

Bjoern Schwer

DNA repair and genome stability

The DNA that makes up the cellular genome is constantly exposed to damage from both endogenous and exogenous sources. Cells must repair DNA damage to maintain their genome. In some biological contexts, cells also rely on DNA breakage and repair to actively alter and rearrange specific parts of their genome. My lab is investigating the mechanisms that mammalian cells use to generate and repair DNA breaks. A major current interest is in how DNA breaks and chromosomal rearrangements in neural lineage cells affect brain function and disorders.