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Drosophila sensory neurons tile the larval body wall, Dr. Chun Han


1650 Owens St., Room 515
(415) 734-4946

Leor Weinberger

How viruses (and cells) make decisions

Our lab is interested in understanding the fundamental principles underlying cell-fate decisions.  We take a unique approach using viruses as model systems, since viruses undergo simplified bifurcations between alternate fates (e.g. active vs. latent).  Using a coupled computational-experimental approach, which relies on quantitative time-lapse microscopy and mathematical modeling, we probe the transcriptional circuits that regulate these alternate fates at the single-cell level.  Ultimately, our goal is to discover new regulatory principles to enable a next-generation of therapeutics that can re-direct viruses and cells down alternate developmental paths.