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Drosophila sensory neurons tile the larval body wall, Dr. Chun Han


Campus Address GH, N-512B Box: 2280
(415) 502-6606

Pamela England

Chemical Neurobiology: Ion Channel Structure-Function, Synaptic Plasticity

One of the most amazing properties of the mammalian central nervous system is its ability to process and store information. Changes in the strength of synapses appear to underlie such learning and memory. Major research efforts in our group are directed towards understanding the molecular basis for this synaptic plasticity. Specific projects in the lab are focused on 1) controlling phosphorylation-dependent signaling cascades using chemical-genetic approaches and, 2) investigating the structure and mechanism of action of ion channels found in the CNS. We use a combination of synthetic organic chemistry, biochemistry, molecular biology and electrophysiology in our research.