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Drosophila sensory neurons tile the larval body wall, Dr. Chun Han


Campus Address: 513 Parnassus, HSW 1464 Box: 0452
(415) 476-6883

Todd Nystul

Epithelial stem cells and cancer

Our laboratory primarily uses the Drosophila ovary as a model for studying the fundamental properties of epithelial stem cells, their associated niche, and the connection between epithelial stem cells and cancer. We are interested in questions such as:  How is stem cell fate maintained within a dynamic epithelial tissue?  What is the nature of the epithelial stem cell niche?  What is the role of epithelial stem cells in reproductive physiology?  How is a healthy population of stem cells maintained throughout adult life?  What can studies of epithelial stem cells teach us about the earliest steps in cancer formation?