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Drosophila sensory neurons tile the larval body wall, Dr. Chun Han

Biochemistry & Molecular Biology

Faculty in the Biochemistry and Molecular Biology (BMB) Group are drawn from several basic and clinical science departments at UCSF. Research within BMB emphasizes biochemical, proteomic, single-molecule and structural approaches to solve a broad range of problems in modern biology. Members of the BMB group, like those in the other three research groups in the Tetrad program, are highly interactive and collaborative. Indeed, a guiding principle of the program is to instill understanding and appreciation of the interactiveness and interrelatedness of diverse research approaches and experimental systems

First Name Last Namesort descending Research Title
David Agard Structure, Function, and Folding of Proteins, Chromosomes, and Centrosomes
Bassem Al-Sady Mechanisms of formation and fidelity of epigenetic elements
Steven Altschuler Systems biology and pharmacology
Raul Andino RNA Viruses, Replication, Pathogenesis and Control
Allan Balmain Mouse Models for the Study of Human Cancer Susceptibility and Cancer Progression
Joseph Bondy-Denomy CRISPR-Cas Biology and Phage-Bacteria Interactions
Katja Brückner Hematopoiesis and cell signaling
Daniele Canzio Transcriptional and post-transcriptional mechanisms generating neural cell-surface diversity
Fred Chang Regulation of Cell Size and Shape
Andy Chang Mechanisms of oxygen and metabolic sensing
Yifan Cheng Structural biology, cryoEM
Seemay Chou Structural and molecular basis of host-microbe interactions
Charles Craik Chemical Biology of Proteases and Their Receptors
Joseph DeRisi Genomics and Infectious Disease
Shawn Douglas DNA nanotechnology
Hana El-Samad Systems Biology of Stress Responses
Pamela England Chemical Neurobiology: Ion Channel Structure-Function, Synaptic Plasticity
Robert Fletterick Nuclear receptors, transcription factors
Stephen Floor What RNA molecules do after they're made
Alan Frankel RNA-protein complexes
James Fraser Macromolecular structure and dynamics
Adam Frost Structural biology
Danica Galonić Fujimori Chromatin, Ribosome, Protein Quality Control
Jennifer Fung Chromosome Synapsis and Recombination Control During Meiosis
Zev Gartner Tissue structure and function
Andrei Goga Oncogene Signaling
Hani Goodarzi Cancer Systems Biology and Translational Genomics
John Gross Control of eukaryotic mRNA stability
Carol Gross Regulation of Gene Expression
Roshanak Irannejad Organelle-based signaling in cardiovascular biology
Yuh Nung Jan Constructing the nervous system
Lily Jan Ion channels
Alexander (Sandy) Johnson Yeast Genetics and Genomics
Martin Kampmann The protein homeostasis network in normal and disease states of human cells
David Kokel High-throughput behavior-based neuroactive drug discovery
Thomas Kornberg Drosophila developmental genetics
Tanja Kortemme Computational protein design, how proteins function in complex contexts
Nevan Krogan Systems Biology
Hao Li Computational Genomics
Joachim Li Regulation of Eukaryotic DNA Replication
Wendell Lim Cell signaling; systems and synthetic biology
Aashish Manglik Structural biophysics of transmembrane signal transduction
Wallace Marshall How Cells Count and Measure
Frank McCormick Ras genes and human cancer
Dan Minor Ion channel structure and chemical biology
David Morgan Protein Machines That Drive the Cell Cycle
Maxence Nachury Trafficking and signaling at the primary cilium
Geeta Narlikar Mechanisms of Regulating Chromatin Structure and Function
Patrick O'Farrell Cell cycle control in development
Barbara Panning Stem Cell Epigenetics
Rushika Perera Reprogramming of cellular metabolic networks in cancer
David Raleigh Developmental biology, lipid signaling and brain tumors
Oren Rosenberg Molecular pathogenesis of bacteria
Davide Ruggero How translational control shapes the proteome in normal and cancer cells
Bjoern Schwer DNA repair and genome stability
Yin Shen Functional genomics and gene regulation
Kevan Shokat Development of Novel Tools to Study Signal Transduction
Daniel Southworth Structure/function of heat shock proteins and protein quality control
Robert Stroud Cellular Signaling and Molecular Mechanisms
Jack Taunton Actin/Membrane Dynamics and Chemical Proteomics
Thea Tlsty Communal-cell interactions in cancer, genetics, epigenetics
Peter Turnbaugh Impact of the human gut microbiome on pharmacology
Ron Vale Molecular Motors
Peter Walter Mechanisms of Organelle Homeostasis
Leor Weinberger How viruses (and cells) make decisions
Orion Weiner Cell polarity and migration
Jonathan Weissman Protein folding, functional genomics
Jeremy Willsey Genetic and Systems Biological Approaches to Understanding Neurodevelopmental Disorders
Lani Wu Systems biology and pharmacology
Keith Yamamoto Signal Transduction and Transcriptional Regulation
Balyn Zaro Proteomic and chemical biology investigations of innate immunity and hematopoiesis