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Dividing human epithelial cell in a late stage of mitosis, Torsten Wittmann

Student Publications

Anand AA, Walter P. Structural insights into ISRIB, a memory-enhancing inhibitor of the integrated stress response. FEBS J. 2020 Jan;287(2):239-245. doi: 10.1111/febs.15073. Epub 2019 Nov 7.
Jeng EE, Bhadkamkar V, Ibe NU, Gause H, Jiang L, Chan J, Jian R, Jimenez-Morales D, Stevenson E, Krogan NJ, Swaney DL, Snyder MP, Mukherjee S, Bassik MC. Systematic Identification of Host Cell Regulators of Legionella pneumophila Pathogenesis Using a Genome-wide CRISPR Screen. Cell Host Microbe. 2019 Oct 9;26(4):551-563.e6. doi: 10.1016/j.chom.2019.08.017. Epub 2019 Sep 17.
Göke A, Schrott S, Mizrak A, Belyy V, Osman C, Walter P. Mrx6 regulates mitochondrial DNA copy number in S. cerevisiae by engaging the evolutionarily conserved Lon protease Pim1. Mol Biol Cell. 2019 Sep 18:mbcE19080470. doi: 10.1091/mbc.E19-08-0470. [Epub ahead of print].
Soto-Perez P, Bisanz JE, Berry JD, Lam KN, Bondy-Denomy J, Turnbaugh PJ. CRISPR-Cas System of a Prevalent Human Gut Bacterium Reveals Hyper-targeting against Phages in a Human Virome Catalog. Cell Host Microbe. 2019 Sep 11;26(3):325-335.e5. doi: 10.1016/j.chom.2019.08.008. Epub 2019 Sep 3.
Kuhn J, Dumont S. Mammalian kinetochores count attached microtubules in a sensitive and switch-like manner. J Cell Biol. 2019 Nov 4;218(11):3583-3596. doi: 10.1083/jcb.201902105. Epub 2019 Sep 6.
van Veen JE, Scherzer M, Boshuizen J, Chu M, Liu A, Landman A, Green S, Trejo C, McMahon M. 18. Mutationally-activated PI3'-kinase-α promotes de-differentiation of lung tumors initiated by the BRAFV600E oncoprotein kinase. Elife. 2019 Aug 27;8. pii: e43668.
Norman TM, Horlbeck MA, Replogle JM, Ge AY, Xu A, Jost M, Gilbert LA, Weissman JS. Exploring genetic interaction manifolds constructed from rich single-cell phenotypes. Science. 2019 Aug 23;365(6455):786-793. doi: 10.1126/science.aax4438. Epub 2019 Aug 8.
Woldemariam S, Nagpal J, Hill T, Li J, Schneider MW, Shankar R, Futey M, Varshney A, Ali N, Mitchell J, Andersen K, Barsi-Rhyne B, Tran A, Costa WS, Krzyzanowski MC, Yu YV, Brueggemann C, Hamilton OS, Ferkey DM, VanHoven M, Sengupta P, Gottschalk A, L'Etoile N. Using a Robust and Sensitive GFP-Based cGMP Sensor for Real-Time Imaging in Intact Caenorhabditis elegans. Genetics. 2019 Sep;213(1):59-77. doi: 10.1534/genetics.119.302392. Epub 2019 Jul 22.
Lopez ML, Lo M, Kung JE, Dudkiewicz M, Jang GM, Von Dollen J, Johnson JR, Krogan NJ, Pawłowski K, Jura N. PEAK3/C19orf35 pseudokinase, a new NFK3 kinase family member, inhibits CrkII through dimerization. Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15495-15504. doi: 10.1073/pnas.1906360116. Epub 2019 Jul 16.

Progam

The academic program for the first year includes three laboratory rotations as well as a core curriculum designed to provide students with a foundation for understanding and conducting research in experimental biology. All students take the four core courses during the first two quarters of the first year, and in the third quarter they choose a sequence of three intensive 2-week minicourses.

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