Journal Club

Wed
10

Journal Club

March
1:00 pm

Remote @ 1:00PM

Series Finale


Fred Chang

“How cells sense they are being squished”

Lomakin AJ et al. The nucleus acts as a ruler tailoring cell responses to spatial constraints. Science. 2020 Oct 16;370(6514):eaba2894. PMID: 33060332.


Carlo Condello

“Immiscible Immunity”

Bosch M et al. Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense. Science. 2020 Oct 16;370(6514):eaay8085. PMID: 33060333.

 

Wed
03

Journal Club

March
1:00 pm

Remote @ 1:00PM

Tim Casey-Clyde
Raleigh Lab

“A cytoskeletal concert orchestrates the first cell division of life”

Scheffler K, Uraji J, Jentoft I, Cavazza T, Mönnich E, Mogessie B, Schuh M. Two mechanisms drive pronuclear migration in mouse zygotes. Nat Commun. 2021 Feb 5;12(1):841. PMID: 33547291; PMCID: PMC7864974.
 

Max Nachury

“β-Coronaviruses take the road less travelled (to poison the world)”

Ghosh S et al. β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway. Cell. 2020 Dec 10;183(6):1520-1535.e14. Epub 2020 Oct 27. PMID: 33157038; PMCID: PMC7590812.
Wed
24

Journal Club

February
1:00 pm

Remote @ 1:00PM

Nathan Cho
Dumont Lab

“You're growing up so fast: Decoupling cell cycle- and cell size-dependent growth with mass measurements”

Mu L, Kang JH, Olcum S, Payer KR, Calistri NL, Kimmerling RJ, Manalis SR, Miettinen TP. Mass measurements during lymphocytic leukemia cell polyploidization decouple cell cycle- and cell size-dependent growth. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):15659-15665. Epub 2020 Jun 24. PMID: 32581119; PMCID: PMC7355023.
 

Rushika Perera

“How organelle metabolism controls skin color”

Adelmann CH, Traunbauer AK, Chen B, Condon KJ, Chan SH, Kunchok T, Lewis CA, Sabatini DM. MFSD12 mediates the import of cysteine into melanosomes and lysosomes. Nature. 2020 Dec;588(7839):699-704. Epub 2020 Nov 18. PMID: 33208952; PMCID: PMC7770032.
Wed
17

Journal Club

February
1:00 pm

Remote @ 1:00PM

Jasmine Sims
Ahituv Lab

“Transcription GPS through DNA Antennas?”

Castellanos M, Mothi N, Muñoz V. Eukaryotic transcription factors can track and control their target genes using DNA antennas. Nat Commun. 2020 Jan 28;11(1):540. PMID: 31992709; PMCID: PMC6987225.
 

David Booth

“Some ciliates spatially synthesize sister strands”

Irwin NAT, Pittis AA, Mathur V, Howe LJ, Keeling PJ, Lynn DH, Bourland WA. The Function and Evolution of Motile DNA Replication Systems in Ciliates. Curr Biol. 2021 Jan 11;31(1):66-76.e6. Epub 2020 Oct 29. PMID: 33125869.
Wed
10

Journal Club

February
1:00 pm

Remote @ 1:00PM

Ali Palla
Fujimori Lab

“Mark of the Outsider: RNA Methylation as a Suppressor of Endogenous Retroviruses”

Chelmicki T et al. m6A RNA methylation regulates the fate of endogenous retroviruses. Nature. 2021 Jan 13. Epub ahead of print. PMID: 33442060.
 

Dyche Mullins

“A twelve-year search for the Loki-est cells in the world”

Imachi H et al. Isolation of an archaeon at the prokaryote-eukaryote interface. Nature. 2020 Jan;577(7791):519-525. Epub 2020 Jan 15. PMID: 31942073; PMCID: PMC7015854.
Wed
03

Journal Club

February
1:00 pm

Remote @ 1:00PM

Liz Bond
Chou Lab

“Fungalien!: Phagosomes Expand via Lysosome Insertion in Response to Fungal Growth”

Westman J, Walpole GFW, Kasper L, Xue BY, Elshafee O, Hube B, Grinstein S. Lysosome Fusion Maintains Phagosome Integrity during Fungal Infection. Cell Host Microbe. 2020 Dec 9;28(6):798-812.e6. Epub 2020 Oct 5. PMID: 33022213.

 

Jocelyne Fadiga
Weiner Lab

“Precision in Promiscuity: Modeling the BMP Ligand/Receptor Specificity”

Su C et al. Ligand-receptor promiscuity enables cellular addressing bioRxiv 2020.12.08.412643.

Wed
27

Journal Club

January
1:00 pm

Remote @ 1:00PM

Nathan Rossen
Julius Lab

“Tunnel Vision: A Hydrophobic Conduit Ushers Membrane Lipids Across the Periplasm”

Isom GL, Coudray N, MacRae MR, McManus CT, Ekiert DC, Bhabha G. LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope. Cell. 2020 Apr 30;181(3):653-664.e19. PMID: 32359438; PMCID: PMC7335425.
 

Martin Kampmann

“Stressing out: A new effector of the unfolded protein response”

You K et al. QRICH1 dictates the outcome of ER stress through transcriptional control of proteostasis. Science. 2021 Jan 1;371(6524):eabb6896. PMID: 33384352.
Wed
20

Journal Club

January
1:00 pm

Remote @ 1:00PM

Kelsey Hennick
Nowakowski Lab

“Coming soon to a gym near you: 3D cortico-motor assembloids flex their muscles in vitro

Andersen J, Revah O, Miura Y, Thom N, Amin ND, Kelley KW, Singh M, Chen X, Thete MV, Walczak EM, Vogel H, Fan HC, Paşca SP. Generation of Functional Human 3D Cortico-Motor Assembloids. Cell. 2020 Dec 23;183(7):1913-1929.e26. Epub 2020 Dec 16. PMID: 33333020.
 

Emily Goldberg

“Essential Role of Macrophages in Heart Health”

Nicolás-Ávila JA et al. A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart. Cell. 2020 Oct 1;183(1):94-109.e23. Epub 2020 Sep 15. PMID: 32937105.
Wed
13

Journal Club

January
1:00 pm

Remote @ 1:00PM

Mustafa Aydogan

“A spatial memory for organelle dynamics”

Abrisch RG, Gumbin SC, Wisniewski BT, Lackner LL, Voeltz GK. Fission and fusion machineries converge at ER contact sites to regulate mitochondrial morphology. J Cell Biol. 2020 Apr 6;219(4):e201911122. PMID: 32328629; PMCID: PMC7147108.
Wed
16

Journal Club

December
1:00 pm

Remote @ 1:00PM

Jessica Mella
Buchwalter Lab

CoroNUPs: Identification of a pore complex in the ER-derived coronavirus replication organelle

Wolff G et al. A molecular pore spans the double membrane of the coronavirus replication organelle. Science. 2020 Sep 11;369(6509):1395-1398. Epub 2020 Aug 6. PMID: 32763915; PMCID: PMC7665310.

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