Journal Club

Wed
15

Journal Club

March
1:00 pm

Deepa Rajan
Marshall Lab

“Resilient sea spiders: a tale of regenerating anuses, gonads, and more”

Brenneis, Georg et al. “The sea spider Pycnogonum litorale overturns the paradigm of the absence of axial regeneration in molting animals.” Proceedings of the National Academy of Sciences of the United States of America vol. 120,5 (2023): e2217272120. doi:10.1073/pnas.2217272120

Taylor Watanabe
Mordes Lab

"Decrypting cryptic exon splicing events: linking TDP-43 proteinopathy and genetic variants in ALS and FTD”

Brown, Anna-Leigh et al. “TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A.” Nature vol. 603,7899 (2022): 131-137. doi:10.1038/s41586-022-04436-3

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Wed
08

Journal Club

March
1:00 pm

Eli Dugan
Marson Lab

"When innate immunity goes awry: Epigenetic silencing mediates establishment of latent HIV reservoir"

Irwan, I.D., Bogerd, H.P. & Cullen, B.R. Epigenetic silencing by the SMC5/6 complex mediates HIV-1 latency. Nat Microbiol 7, 2101–2113 (2022).  doi: https://doi.org/10.1038/s41564-022-01264-z

Matt Howard
Coyote-Maestas and Manglik Labs

"ER stress transforms random olfactory receptor choice into axon targeting precision "

Shayya, Hani J et al. “ER stress transforms random olfactory receptor choice into axon targeting precision.” Cell vol. 185,21 (2022): 3896-3912.e22. doi:10.1016/j.cell.2022.08.025

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Wed
01

Journal Club

March
1:00 pm

Chloe Ghent
Rotations

"Betrayal by Ubiquitin"
 
Su, Wei et al. “Tripartite motif-containing protein 46 accelerates influenza A H7N9 virus infection by promoting K48-linked ubiquitination of TBK1.” Virology journal vol. 19,1 176. 3 Nov. 2022, doi:10.1186/s12985-022-01907-x

 

Fred Chang

"Life in a high pressure environment: gauging pressures inside cells in an embryo"
 

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Wed
22

Journal Club

February
1:00 pm

Emmy Delaney
Morgan Lab

"Nuclear Tug-Of-War: How Mechanical Forces Drive Mitotic Entry"

Dantas, M., Oliveira, A., Aguiar, P., Maiato, H., & Ferreira, J. G. (2022). Nuclear tension controls mitotic entry by regulating cyclin B1 nuclear translocation. The Journal of cell biology, 221(12), e202205051. https://doi.org/10.1083/jcb.202205051’


Elphège Nora

"Hijacking of transcriptional condensates by endogenous retroviruses"

Asimi, V., Sampath Kumar, A., Niskanen, H. et al. Hijacking of transcriptional condensates by endogenous retroviruses. Nat Genet 54, 1238–1247 (2022). https://doi.org/10.1038/s41588-022-01132-w

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Wed
15

Journal Club

February
1:00 pm

David Sanchez Godinez Orion Lab
 

"Fat2 polarizes the WAVE complex in trans to align cell protrusions for collective migration"

Audrey Miller Williams, Seth Donoughe, Edwin Munro, Sally Horne-Badovinac (2022) Fat2 polarizes the WAVE complex in trans to align cell protrusions for collective migration eLife 11:e78343 https://doi.org/10.7554/eLife.78343

Wed
08

Journal Club

February
1:00 pm

Julia Kim
Marshall Lab

"Take a Break: How Oocytes balance oxidative stress with metabolic load"

Rodríguez-Nuevo, Aida et al. “Oocytes maintain ROS-free mitochondrial metabolism by suppressing complex I.” Nature vol. 607,7920 (2022): 756-761. doi:10.1038/s41586-022-04979-5

Carlo Condello

"Drug-Resistant Human Microglia Reinvigorate Mouse Brain. "

Chadarevian, Jean Paul et al. “Engineering an inhibitor-resistant human CSF1R variant for microglia replacement.” The Journal of experimental medicine vol. 220,3 (2023): e20220857. doi:10.1084/jem.20220857

 

Wed
01

Journal Club

February
1:00 pm

Caroline Wilson
Gilbert Lab

"To Me or not to Me: Charting DNA methyltransferase activity through base editor scanning. "

Lue, N.Z., Garcia, E.M., Ngan, K.C. et al. Base editor scanning charts the DNMT3A activity landscape. Nat Chem Biol (2022). https://doi.org/10.1038/s41589-022-01167-4

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Wed
18

Journal Club

January
1:00 pm

Jennifer Le
Gartner Lab

"Cell-ebrating cellular self-organization"

Bao, M., Cornwall-Scoones, J., Sanchez-Vasquez, E. et al. Stem cell-derived synthetic embryos self-assemble by exploiting cadherin codes and cortical tension. Nat Cell Biol 24, 1341–1349 (2022). https://doi.org/10.1038/s41556-022-00984-y


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Wed
11

Journal Club

January
1:00 pm

Philipp Huettemann
Kortemme Lab

"Arts and crafts for scientists: synthetic multicellular patterning"

Kim, H., Skinner, D.J., Glass, D.S. et al. 4-bit adhesion logic enables universal multicellular interface patterning. Nature 608, 324–329 (2022). https://doi.org/10.1038/s41586-022-04944-2

Danica Galonić Fujimori

"Looped in: Oncogenic fusions drive phase separation and cancer development"

Ahn et al, Phase separation drives aberrant chromatin looping and cancer development. Nature 2021, 595:591. DOI: 10.1038/s41586-021-03662-5

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Wed
09

Journal Club

November
1:00 pm

Tracy Knight
Buchwalter Lab

“The Mitosis Roundup: Microtubule disassembly triggers cell rounding in early mitosis”

Leguay, Kévin et al. “Interphase microtubule disassembly is a signaling cue that drives cell rounding at mitotic entry.” The Journal of cell biology vol. 221,6 (2022): e202109065. doi:10.1083/jcb.202109065

Gabriel Viramontes
Booth Lab

"If the food is right, we belong together: regulated life cycles cue us into the evolution of multicellularity"

Alternating selection for dispersal and multicellularity favors regulated life cycles
Julien Barrere, Piyush Nanda, Andrew W. Murray
bioRxiv 2022.10.14.512267; doi: https://doi.org/10.1101/2022.10.14.512267

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