Chloe Ghent
Rotations
Fred Chang
Class Capture:
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Eli Dugan
Marson Lab
"When innate immunity goes awry: Epigenetic silencing mediates establishment of latent HIV reservoir"
Irwan, I.D., Bogerd, H.P. & Cullen, B.R. Epigenetic silencing by the SMC5/6 complex mediates HIV-1 latency. Nat Microbiol 7, 2101–2113 (2022). doi: https://doi.org/10.1038/s41564-022-01264-z
Matt Howard
Coyote-Maestas and Manglik Labs
"ER stress transforms random olfactory receptor choice into axon targeting precision "
Shayya, Hani J et al. “ER stress transforms random olfactory receptor choice into axon targeting precision.” Cell vol. 185,21 (2022): 3896-3912.e22. doi:10.1016/j.cell.2022.08.025
Class Capture:
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Deepa Rajan
Marshall Lab
“Resilient sea spiders: a tale of regenerating anuses, gonads, and more”
Brenneis, Georg et al. “The sea spider Pycnogonum litorale overturns the paradigm of the absence of axial regeneration in molting animals.” Proceedings of the National Academy of Sciences of the United States of America vol. 120,5 (2023): e2217272120. doi:10.1073/pnas.2217272120
Taylor Watanabe
Mordes Lab
"Decrypting cryptic exon splicing events: linking TDP-43 proteinopathy and genetic variants in ALS and FTD”
Brown, Anna-Leigh et al. “TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A.” Nature vol. 603,7899 (2022): 131-137. doi:10.1038/s41586-022-04436-3
Class Capture:
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Caroline Wilson
Gilbert Lab
"To Me or not to Me: Charting DNA methyltransferase activity through base editor scanning. "
Lue, N.Z., Garcia, E.M., Ngan, K.C. et al. Base editor scanning charts the DNMT3A activity landscape. Nat Chem Biol (2022). https://doi.org/10.1038/s41589-022-01167-4
Class Capture: https://lecture.ucsf.edu/ets/Channel/10af69c3191d4e96a72eab2677722bef5f/
Julia Kim
Marshall Lab
"Take a Break: How Oocytes balance oxidative stress with metabolic load"
Rodríguez-Nuevo, Aida et al. “Oocytes maintain ROS-free mitochondrial metabolism by suppressing complex I.” Nature vol. 607,7920 (2022): 756-761. doi:10.1038/s41586-022-04979-5
Carlo Condello
"Drug-Resistant Human Microglia Reinvigorate Mouse Brain. "
Chadarevian, Jean Paul et al. “Engineering an inhibitor-resistant human CSF1R variant for microglia replacement.” The Journal of experimental medicine vol. 220,3 (2023): e20220857. doi:10.1084/jem.20220857
David Sanchez Godinez
Orion Lab
"Fat2 polarizes the WAVE complex in trans to align cell protrusions for collective migration"
Audrey Miller Williams, Seth Donoughe, Edwin Munro, Sally Horne-Badovinac (2022) Fat2 polarizes the WAVE complex in trans to align cell protrusions for collective migration eLife 11:e78343 https://doi.org/10.7554/eLife.78343
Emmy Delaney
Morgan Lab
"Nuclear Tug-Of-War: How Mechanical Forces Drive Mitotic Entry"
Dantas, M., Oliveira, A., Aguiar, P., Maiato, H., & Ferreira, J. G. (2022). Nuclear tension controls mitotic entry by regulating cyclin B1 nuclear translocation. The Journal of cell biology, 221(12), e202205051. https://doi.org/10.1083/jcb.202205051’
Elphège Nora
"Hijacking of transcriptional condensates by endogenous retroviruses"
Asimi, V., Sampath Kumar, A., Niskanen, H. et al. Hijacking of transcriptional condensates by endogenous retroviruses. Nat Genet 54, 1238–1247 (2022). https://doi.org/10.1038/s41588-022-01132-w
Class Capture:
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Jennifer Le
Gartner Lab
"Cell-ebrating cellular self-organization"
Bao, M., Cornwall-Scoones, J., Sanchez-Vasquez, E. et al. Stem cell-derived synthetic embryos self-assemble by exploiting cadherin codes and cortical tension. Nat Cell Biol 24, 1341–1349 (2022). https://doi.org/10.1038/s41556-022-00984-y
Class Capture:
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Philipp Huettemann
Kortemme Lab
"Arts and crafts for scientists: synthetic multicellular patterning"
Kim, H., Skinner, D.J., Glass, D.S. et al. 4-bit adhesion logic enables universal multicellular interface patterning. Nature 608, 324–329 (2022). https://doi.org/10.1038/s41586-022-04944-2
Danica Galonić Fujimori
"Looped in: Oncogenic fusions drive phase separation and cancer development"
Ahn et al, Phase separation drives aberrant chromatin looping and cancer development. Nature 2021, 595:591. DOI: 10.1038/s41586-021-03662-5
Class Capture: https://lecture.ucsf.edu/ets/Channel/10af69c3191d4e96a72eab2677722bef5f/
Kenya Bonitto
Ruggero Lab
“Trick or translate: Spooky Splicing in
Myc-driven oncogenesis”
Cieśla, Maciej, et al. “Oncogenic Translation Directs Spliceosome Dynamics Revealing an Integral Role for SF3A3 in Breast Cancer.” Molecular Cell, vol. 81, no. 7, Elsevier BV, Apr. 2021, pp. 1453-1468.e12. Crossref, doi:10.1016/j.molcel.2021.01.034.
Angela Phillips
“Epistatic Drift Causes Gradual Decay of Predictability in Protein Evolution”
Park, Yeonwoo, et al. “Epistatic Drift Causes Gradual Decay of Predictability in Protein Evolution.” Science, vol. 376, no. 6595, American Association for the Advancement of Science (AAAS), 20 May 2022, pp. 823–830. Crossref, doi:10.1126/science.abn6895.
Class Capture: https://lecture.ucsf.edu/ets/Channel/9cb5d8c3d8ec44b19c54915aeec32dfb5f/