Journal Club
March1:00 pm
Deepa Rajan
Marshall Lab
“Resilient sea spiders: a tale of regenerating anuses, gonads, and more”
Brenneis, Georg et al. “The sea spider Pycnogonum litorale overturns the paradigm of the absence of axial regeneration in molting animals.” Proceedings of the National Academy of Sciences of the United States of America vol. 120,5 (2023): e2217272120. doi:10.1073/pnas.2217272120
Taylor Watanabe
Mordes Lab
"Decrypting cryptic exon splicing events: linking TDP-43 proteinopathy and genetic variants in ALS and FTD”
Brown, Anna-Leigh et al. “TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A.” Nature vol. 603,7899 (2022): 131-137. doi:10.1038/s41586-022-04436-3
Class Capture:
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Journal Club
March1:00 pm
Eli Dugan
Marson Lab
"When innate immunity goes awry: Epigenetic silencing mediates establishment of latent HIV reservoir"
Irwan, I.D., Bogerd, H.P. & Cullen, B.R. Epigenetic silencing by the SMC5/6 complex mediates HIV-1 latency. Nat Microbiol 7, 2101–2113 (2022). doi: https://doi.org/10.1038/s41564-022-01264-z
Matt Howard
Coyote-Maestas and Manglik Labs
"ER stress transforms random olfactory receptor choice into axon targeting precision "
Shayya, Hani J et al. “ER stress transforms random olfactory receptor choice into axon targeting precision.” Cell vol. 185,21 (2022): 3896-3912.e22. doi:10.1016/j.cell.2022.08.025
Class Capture:
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Journal Club
March1:00 pm
Chloe Ghent
Rotations
Fred Chang
Class Capture:
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Journal Club
February1:00 pm
Emmy Delaney
Morgan Lab
"Nuclear Tug-Of-War: How Mechanical Forces Drive Mitotic Entry"
Dantas, M., Oliveira, A., Aguiar, P., Maiato, H., & Ferreira, J. G. (2022). Nuclear tension controls mitotic entry by regulating cyclin B1 nuclear translocation. The Journal of cell biology, 221(12), e202205051. https://doi.org/10.1083/jcb.202205051’
Elphège Nora
"Hijacking of transcriptional condensates by endogenous retroviruses"
Asimi, V., Sampath Kumar, A., Niskanen, H. et al. Hijacking of transcriptional condensates by endogenous retroviruses. Nat Genet 54, 1238–1247 (2022). https://doi.org/10.1038/s41588-022-01132-w
Class Capture:
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Journal Club
February1:00 pm
David Sanchez Godinez
"Fat2 polarizes the WAVE complex in trans to align cell protrusions for collective migration"
Audrey Miller Williams, Seth Donoughe, Edwin Munro, Sally Horne-Badovinac (2022) Fat2 polarizes the WAVE complex in trans to align cell protrusions for collective migration eLife 11:e78343 https://doi.org/10.7554/eLife.78343
Journal Club
February1:00 pm
Julia Kim
Marshall Lab
"Take a Break: How Oocytes balance oxidative stress with metabolic load"
Rodríguez-Nuevo, Aida et al. “Oocytes maintain ROS-free mitochondrial metabolism by suppressing complex I.” Nature vol. 607,7920 (2022): 756-761. doi:10.1038/s41586-022-04979-5
Carlo Condello
"Drug-Resistant Human Microglia Reinvigorate Mouse Brain. "
Chadarevian, Jean Paul et al. “Engineering an inhibitor-resistant human CSF1R variant for microglia replacement.” The Journal of experimental medicine vol. 220,3 (2023): e20220857. doi:10.1084/jem.20220857
Journal Club
February1:00 pm
Caroline Wilson
Gilbert Lab
"To Me or not to Me: Charting DNA methyltransferase activity through base editor scanning. "
Lue, N.Z., Garcia, E.M., Ngan, K.C. et al. Base editor scanning charts the DNMT3A activity landscape. Nat Chem Biol (2022). https://doi.org/10.1038/s41589-022-01167-4
Class Capture: https://lecture.ucsf.edu/ets/Channel/10af69c3191d4e96a72eab2677722bef5f/
Journal Club
January1:00 pm
Jennifer Le
Gartner Lab
"Cell-ebrating cellular self-organization"
Bao, M., Cornwall-Scoones, J., Sanchez-Vasquez, E. et al. Stem cell-derived synthetic embryos self-assemble by exploiting cadherin codes and cortical tension. Nat Cell Biol 24, 1341–1349 (2022). https://doi.org/10.1038/s41556-022-00984-y
Class Capture:
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Journal Club
January1:00 pm
Philipp Huettemann
Kortemme Lab
"Arts and crafts for scientists: synthetic multicellular patterning"
Kim, H., Skinner, D.J., Glass, D.S. et al. 4-bit adhesion logic enables universal multicellular interface patterning. Nature 608, 324–329 (2022). https://doi.org/10.1038/s41586-022-04944-2
Danica Galonić Fujimori
"Looped in: Oncogenic fusions drive phase separation and cancer development"
Ahn et al, Phase separation drives aberrant chromatin looping and cancer development. Nature 2021, 595:591. DOI: 10.1038/s41586-021-03662-5
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Journal Club
November1:00 pm
Tracy Knight
Buchwalter Lab
“The Mitosis Roundup: Microtubule disassembly triggers cell rounding in early mitosis”
Leguay, Kévin et al. “Interphase microtubule disassembly is a signaling cue that drives cell rounding at mitotic entry.” The Journal of cell biology vol. 221,6 (2022): e202109065. doi:10.1083/jcb.202109065
Gabriel Viramontes
Booth Lab
"If the food is right, we belong together: regulated life cycles cue us into the evolution of multicellularity"
Alternating selection for dispersal and multicellularity favors regulated life cycles
Julien Barrere, Piyush Nanda, Andrew W. Murray
bioRxiv 2022.10.14.512267; doi: https://doi.org/10.1101/2022.10.14.512267
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