Kenya Bonitto
Ruggero Lab

“Trick or translate: Spooky Splicing in
Myc-driven oncogenesis”

Cieśla, Maciej, et al. “Oncogenic Translation Directs Spliceosome Dynamics Revealing an Integral Role for SF3A3 in Breast Cancer.” Molecular Cell, vol. 81, no. 7, Elsevier BV, Apr. 2021, pp. 1453-1468.e12. Crossref, doi:10.1016/j.molcel.2021.01.034.

Angela Phillips

“Epistatic Drift Causes Gradual Decay of Predictability in Protein Evolution”

Park, Yeonwoo, et al. “Epistatic Drift Causes Gradual Decay of Predictability in Protein Evolution.” Science, vol. 376, no. 6595, American Association for the Advancement of Science (AAAS), 20 May 2022, pp. 823–830. Crossref, doi:10.1126/science.abn6895.

Class Capture: https://lecture.ucsf.edu/ets/Channel/9cb5d8c3d8ec44b19c54915aeec32dfb5f/

Camille Derderian

Reiter Lab

“These boots were made for destroying: Kinesins tear up microtubules as they walk”

Budaitis, Breane G et al. “A kinesin-1 variant reveals motor-induced microtubule damage in cells.” Current biology : CB vol. 32,11 (2022): 2416-2429.e6. doi:10.1016/j.cub.2022.04.020

CJ San Felipe
Fraser Lab

“The Real SLiM Shady? Sequence- and chemical specificity define the functional landscape of intrinsically disordered regions”

Iris Langstein-Skora, Andrea Schmid, Ryan J. Emenecker, Mary O.G. Richardson, Maximilian J. Götz, Sarah K. Payer, Philipp Korber, Alex S. Holehouse. Sequence- and chemical specificity define the functional landscape of intrinsically disordered regions. bioRxiv 2022.02.10.480018
 
Margaux Pinney
 
"Breaking the Code: tryptophan depletion results in tryptophan-to-phenylalanine substitutants"
 
Pataskar, A., Champagne, J., Nagel, R. et al. Tryptophan depletion results in tryptophan-to-phenylalanine substitutants. Nature (2022).

Candace Chan
Ahituv Lab

“Knowing when to fold: Exploring association of G4s in promoters and transcriptional activity ”

Shen J, Varshney D, Simeone A, Zhang X, Adhikari S, Tannahill D, Balasubramanian S. Promoter G-quadruplex folding precedes transcription and is controlled by chromatin. Genome Biol. 2021 May 7;22(1):143. PMID: 33962653; PMCID: PMC8103603.
 
Andrew Yang
 
"Building a better home for the brain"
 
Martin M et al. Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders. Science. 2022 Feb 18;375(6582):eabm4459. Epub 2022 Feb 18. PMID: 35175798.

Addie Dwyer Cady
Raleigh Lab

“Employing proteomics to improve targeted brain cancer therapies”

Petralia F et al; Children’s Brain Tumor Network; Clinical Proteomic Tumor Analysis Consortium. Integrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain Cancer. Cell. 2020 Dec 23;183(7):1962-1985.e31. Epub 2020 Nov 25. PMID: 33242424; PMCID: PMC8143193.
 
Abby Buchwalter
 
"When stiffness is a signal: mechanical signaling from the extracellular matrix to the nuclear lamina controls Wnt signaling and cell fate"
 
Tang Y, Zhu L, Cho JS, Li XY, Weiss SJ. Matrix remodeling controls a nuclear lamin A/C-emerin network that directs Wnt-regulated stem cell fate. Dev Cell. 2022 Feb 4:S1534-5807(22)00040-5. Epub ahead of print. PMID: 35150612.

Trase Aguigam
J. Gross/Narlikar Lab

“What’s the FUS? Paramagnetic spectroscopy reveals compaction of the RNA-binding protein FUS upon phase separation.”

Emmanouilidis L, Esteban-Hofer L, Damberger FF, de Vries T, Nguyen CKX, Ibáñez LF, Mergenthal S, Klotzsch E, Yulikov M, Jeschke G, Allain FH. NMR and EPR reveal a compaction of the RNA-binding protein FUS upon droplet formation. Nat Chem Biol. 2021 May;17(5):608-614. Epub 2021 Mar 8. PMID: 33686294.
 
Todd Nystul
 
"O, wind, if winter comes, can spring be far behind?"
 
Easwaran S, Van Ligten M, Kui M, Montell DJ. Enhanced germline stem cell longevity in Drosophila diapause. Nat Commun. 2022 Feb 7;13(1):711. PMID: 35132083.

Alexis Villani
Bondy-Denomy Lab

“My PriON will go ON: A prion's epigenetic role in an active chromatin state”

Harvey ZH, Chakravarty AK, Futia RA, Jarosz DF. A Prion Epigenetic Switch Establishes an Active Chromatin State. Cell. 2020 Mar 5;180(5):928-940.e14. Epub 2020 Feb 27. PMID: 32109413; PMCID: PMC7195540.
 
Armando Martinez
McCormick Lab
 
"Good Cop, Bad Cop. Cop1 modulates macrophage infiltration"
 
Xiaoqing Wang et al. In Vivo CRISPR Screens Identify E3 Ligase Cop1 as a Modulator of Macrophage Infiltration and Cancer Immunotherapy Target. bioRxiv 2020.12.09.418012.

GH N114 (indoor masking required) and Class Capture

Kim Meneses
Gartner Lab

“To 3D or not to 3D: the new wave of tissue imaging”

Kuett, L., Catena, R., Özcan, A. et al. Three-dimensional imaging mass cytometry for highly multiplexed molecular and cellular mapping of tissues and the tumor microenvironment. Nat Cancer 3, 122–133 (2022).
 
Joe Bondy-Denomy
 
"Hot Cell Death FTW"
 
Johnson AG, Wein T, Mayer ML, Duncan-Lowey B, Yirmiya E, Oppenheimer-Shaanan Y, Amitai G, Sorek R, Kranzusch PJ. Bacterial gasdermins reveal an ancient mechanism of cell death. Science. 2022 Jan 14;375(6577):221-225. Epub 2022 Jan 13. PMID: 35025633.

GH N114 (indoor masking required) and Class Capture

Alex Hong
Bondy-Denomy Lab

“Cat got your tongue?: Toxoplasma gondii latent infection is maintained by bradyzoite's type I interferon suppression”

Seizova S, Ruparel U, Garnham AL, Bader SM, Uboldi AD, Coffey MJ, Whitehead LW, Rogers KL, Tonkin CJ. Transcriptional modification of host cells harboring Toxoplasma gondii bradyzoites prevents IFN gamma-mediated cell death. Cell Host Microbe. 2021 Dec 16:S1931-3128(21)00518-7. Epub ahead of print. PMID: 34921775.

 
Max Nachury
 
"Shaking the dogma from within: is there local protein synthesis inside cilia?"
 
Hao K, Chen Y, Yan X, Zhu X. Cilia locally synthesize proteins to sustain their ultrastructure and functions. Nat Commun. 2021 Nov 30;12(1):6971. PMID: 34848703; PMCID: PMC8632896.